1 Psychology and human development1.11 Underlying concepts in human development

1.11.3 Methodology for studying development

2 min read1 figure

Written by Resident Doctor Committee · Published

Why design matters

Age cannot be randomly assigned, so comparing age groups only describes differences. Change, stability and sequence need repeated observations of the same people.

Cross-sectional and longitudinal designs

Design

Method

Strengths

Weaknesses

Cross-sectional

Separate age groups measured once

Quick and cheap, with no years of follow-up or attrition

Age is confounded with birth cohort; shows no within-person change, sequence or cause

Longitudinal

The same people measured repeatedly

Temporal order, within-person change, stability and sequence

Time, cost, selective attrition, practice effects

The longitudinal cohort follows the same children at ages 5, 9 and 15 and so shows change within each child, while the cross-sectional survey measures three groups once, each from a different birth cohort, so age is confounded with cohort. Drawn for MRCPsychiatrist
  • The chief advantage of a cross-sectional design is speed and low cost, not causal, individual-trajectory or age-versus-cohort inference.

  • A longitudinal design is needed to test whether an early characteristic predicts a later outcome and whether a third variable moderates that link.

  • The British birth cohorts and the Dunedin study follow people over time to link early experience with later outcomes.

Natural experiments

  • A natural or quasi-experiment compares groups defined by an exposure that the investigators did not allocate and that was not randomised, such as a policy change, famine or adoption after deprivation.

  • It strengthens causal inference about an early exposure but cannot exclude residual confounding.

  • The English and Romanian Adoptees study compared outcomes after different lengths of institutional deprivation, but adoption timing was not random.

  • A timing pattern in outcomes from such a study can support a sensitive period.

Judging causation

Design

What it supports

Cross-sectional correlation

Association without temporal order

Prospective longitudinal

Temporal order, with possible confounding

Natural experiment or genetically informative design

Stronger inference when assumptions hold

Randomised intervention trial

Causal treatment effects

  • Exposure before outcome, a dose-response pattern and replication strengthen an association, but none alone proves causation.

Adverse childhood experiences (ACEs)

  • The original ACE study, by the Centers for Disease Control and Prevention (CDC) and Kaiser Permanente, linked cumulative childhood adversity with later mental and physical ill health.

  • Risk rises in a graded, dose-response way with the number of adversity categories experienced, not with the type of adversity.

  • The same gradient holds for suicide attempt and for cumulative maltreatment.

  • Parental imprisonment is a recognised ACE category, and ACEs are linked to later delinquency and offending.

  • Retrospective reports risk recall bias; prospective evidence adds confidence, though individual outcomes vary.