2 Neuroscience2.10 Neurodevelopment and neuroplasticity

2.10.5 Intelligence and learning disability

7 min read4 figures

Written by Resident Doctor Committee · Published

General intelligence

Intelligence supports reasoning, learning, problem solving and adaptation. Attainment also reflects education, language, opportunity and health.

  • Positive manifold is the finding that scores on different cognitive tests correlate positively.

  • Spearman's two-factor theory used factor analysis of these correlated scores to give a general factor (g) common to all tests plus a factor specific to each test (s).

  • The g factor describes shared variance in scores, not a single brain structure.

  • Heritability of intelligence generally rises with age while shared family effects decline.

  • Heritability describes variance in a population, not causation in an individual or differences between groups.

Thurstone's primary mental abilities

Thurstone described seven correlated primary abilities. Labels from Cattell and Horn, the Wechsler indices or Galton are not on his list.

Ability

What it is

Verbal comprehension

Understanding the meaning of words and text

Word fluency

Speed of producing words to a rule

Perceptual speed

Rapid, accurate comparison of visual detail to find likenesses and differences

Spatial visualisation

Mentally turning objects in space

Number facility

Handling numbers

Associative memory

The learned link that lets one member of an arbitrary pair retrieve the other

Reasoning

Inductive reasoning

Fluid and crystallised intelligence

Cattell and Horn separated two broad abilities.

Feature

Fluid reasoning (Gf)

Crystallised intelligence (Gc)

Task

Reasoning on novel material without relying on stored knowledge

Knowledge and skill acquired through education and culture

Ageing

Peaks in early adulthood, then falls

Comparatively preserved, or grows into later life

Brain damage

More vulnerable

Survives diffuse injury reasonably well

Follow the two curves: fluid reasoning peaks in early adulthood and then falls, while crystallised intelligence keeps rising into the sixties and holds up comparatively well into later life. Drawn for MRCPsychiatrist

The Cattell-Horn-Carroll model

The Cattell-Horn-Carroll (CHC) model is a three-stratum hierarchy, and current Wechsler scales are structured on it.

Stratum

Level

Example

I

Narrow, task-level abilities

Quantitative reasoning

II

Broad abilities

Gf, Gc

III

General intelligence

g

  • Quantitative reasoning is a narrow ability grouped under fluid reasoning, which itself loads on g.

Read the tree from the bottom up: quantitative reasoning is a narrow stratum I ability under fluid reasoning (Gf), a stratum II broad ability that in turn loads on g at stratum III. Drawn for MRCPsychiatrist

Gardner and Sternberg

Gardner's intelligences reach beyond reasoning to music, movement and self-knowledge, whereas Sternberg keeps to analytical, creative and practical thinking.

Gardner

  • Multiple intelligences include musical, bodily-kinaesthetic, interpersonal and intrapersonal domains.

  • Intrapersonal intelligence is knowing and regulating one's own emotions, motives and behaviour.

  • Emotional intelligence is a separate model from Salovey and Mayer, popularised by Goleman.

  • The main scientific objection is that the intelligences overlap and are not empirically separable, since tests of them correlate with one another and with general ability.

Sternberg

Sternberg's triarchic theory of successful intelligence balances three abilities in a sociocultural context.

Ability

What it does

Analytical

Compares, evaluates and judges

Creative

Imagines, invents and discovers

Practical

Applies, implements and adapts; includes tacit knowledge of unwritten rules and adapting to a changed environment

  • Conventional intelligence quotient (IQ) tests and academic examinations capture mainly analytical intelligence and miss creative and practical intelligence.

Measuring IQ

Worker

Contribution

Binet

Mental age: the age level that a child's test performance matches

Stern

Ratio IQ: mental age divided by chronological age

Terman

Stanford-Binet IQ: the ratio multiplied by 100

Wechsler

Deviation IQ: performance compared with age-group norms

  • Adult IQ is a deviation score from an age-normed instrument such as the Wechsler Adult Intelligence Scale (WAIS), not the obsolete ratio formula.

  • IQ is normed to a symmetrical normal curve with mean 100 and standard deviation (SD) 15, so mean and median coincide and about half the population scores above 100.

  • About two-thirds of people score 85 to 115 and about 2% score below 70.

  • Reliability is good for full-scale and index scores but poor for single subtests, so report a confidence interval near thresholds.

On the IQ scale each sigma step is 15 points, so the two dark central bands (85 to 115) hold about two thirds of people and the area beyond minus 2 sigma (below 70) holds about 2%. M. W. Toews, CC BY 2.5, via Wikimedia Commons

The Flynn effect

  • The Flynn effect is the secular rise in mean IQ across generations of whole populations, so old norms become obsolete and tests need re-norming.

  • An ageing test flatters current ability: a lower IQ on a newer edition with unchanged ability means outdated norms inflated the earlier score.

The Wechsler scales

Scale

Ages

Wechsler Preschool and Primary Scale of Intelligence (WPPSI)

Preschool children

Wechsler Intelligence Scale for Children (WISC-V)

6 to 16, normed to 16 years 11 months

WAIS-IV

16 years 0 months to 90

  • The adult scale starts at 16, not 18.

Test

What it measures

WAIS

Current general intelligence across domains as a Full Scale IQ; full battery of 60 to 90 minutes

Wechsler Abbreviated Scale of Intelligence (WASI)

Brief four-subtest screen of about 30 minutes

National Adult Reading Test (NART)

Premorbid ability, estimated from word reading

Memory scales, adaptive behaviour scales, single-domain neuropsychological tests

One area only, not general intelligence

Raven's Progressive Matrices

General intelligence by abstract pattern completion, with minimal reliance on language

An example item from Raven's Progressive Matrices, a grid of geometric patterns with one piece missing, used to assess nonverbal reasoning. User:Life of Riley, CC BY-SA 3.0, via Wikimedia Commons
  • Diagnosing intellectual disability needs the full age-normed scale (WISC-V for 6 to 16, WAIS-IV from 16), not a screening estimate such as the WASI-II.

WAIS-IV indices

Earlier editions split ability into a verbal IQ and a performance IQ that combined into a full-scale IQ. The WAIS-IV replaced them with four indices that combine into a Full Scale IQ.

Index

Subtests

What it reflects

Verbal Comprehension

Similarities, Vocabulary, Information

Verbal reasoning and crystallised knowledge

Perceptual Reasoning

Block Design, Matrix Reasoning

Non-verbal visual pattern and spatial reasoning

Working Memory

Digit Span, Arithmetic

Holding and manipulating information

Processing Speed

Coding, Symbol Search, Cancellation

Sheer speed on timed pencil tasks

  • The General Ability Index is built from Verbal Comprehension and Perceptual Reasoning only, so it is the better reasoning estimate when working memory and processing speed are disproportionately low.

  • A Full Scale IQ below the General Ability Index points to a lowered Working Memory or Processing Speed Index.

  • The Processing Speed Index is disproportionately lowered by the psychomotor slowing of depression.

Hold and don't-hold subtests

  • Hold subtests draw on old, overlearned knowledge and survive brain damage and ageing.

  • Don't-hold subtests, such as Digit Symbol, need speed, working memory and new learning, and decline early.

  • A current IQ within one SD of the mean (85 to 115) can still represent decline when set against a reading-based premorbid estimate.

Intellectual disability

Intellectual disability needs three joint criteria:

  1. Intellectual functioning is well below average, typically around two SDs below the mean.

  2. The person has deficits in adaptive functioning.

  3. Onset is in the developmental period.

  • UK "learning disability" means intellectual disability, whereas "learning difficulty" often means a specific difficulty such as dyslexia.

  • Prevalence is about 1 to 2%.

Severity

ICD-11 (International Classification of Diseases, 11th revision) grades a disorder of intellectual development using both intellectual functioning and adaptive behaviour.

Grade

Typical assessment profile

Everyday support

Mild

Intellectual and adaptive functioning about 2 to 3 SDs below the mean

Basic self-care often achieved; support with complex tasks

Moderate

About 3 to 4 SDs below the mean

Considerable, consistent support

Severe

About 4 or more SDs below the mean

Limited language and daily support; some self-care can be learned

Profound

Distinguished from severe by adaptive behaviour

Very limited communication and extensive daily support

  • Borderline intellectual functioning (IQ about 70 to 84) lies above the disability range.

  • Bands are told apart by the level of language and literacy and the support needed for self-care, work and independent living.

  • Mild intellectual disability means largely independent daily living, and many people work.

  • IQ alone does not define severity or support needs, and measurement uncertainty must be allowed for.

Adaptive functioning

Domain

Examples

Conceptual

Language, literacy, money, time, number, academic skills

Social

Interpersonal skill, social judgement, communication, friendship, gullibility

Practical

Personal care, health and safety, travel, occupation, household tasks

  • Adaptive functioning is assessed through informants and everyday performance, and vulnerability to exploitation is assessed directly.

Causes

Identifiable biological causes are commoner in severe and profound disability, while mild disability often reflects interacting genetic and environmental influences.

Category

Examples

Chromosomal

Down, fragile X, Williams, Prader-Willi, Angelman, 22q11.2 deletion

Single-gene and metabolic

Phenylketonuria, congenital hypothyroidism, tuberous sclerosis, Rett

Prenatal

Alcohol, valproate, rubella, cytomegalovirus, toxoplasmosis, iodine deficiency

Perinatal

Prematurity, hypoxia, haemorrhage, kernicterus, hypoglycaemia, sepsis

Postnatal

Brain infection, injury, lead, malnutrition, status epilepticus, deprivation

Mental health

  • Psychiatric disorders are commoner, and epilepsy risk rises with severity.

  • Diagnostic overshadowing is misattributing new symptoms to the disability itself.

  • Depression may present as lost skills, withdrawal, irritability or self-injury.