9 Child and adolescent psychiatry9.5 Physical health and psychiatric disorder

9.5 Psychiatric disorder and physical illness in children

2 min read2 figures

Written by Resident Doctor Committee · Published

Distress expressed through the body

  • Children often voice distress through pain, fatigue or other physical symptoms. These symptoms are real and have physical, psychological and social causes.

  • Functional neurological disorder is diagnosed on positive clinical features, not on normal tests or a history of stress.

Chronic fatigue syndrome in young people

  • Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is diagnosed in a child or young person under National Institute for Health and Care Excellence (NICE) guidance when the core symptoms have lasted three months and no other condition explains them.

  • Post-exertional worsening points to ME/CFS, so do not assume that deconditioning keeps the fatigue going.

  • Outlook is better than in adults: most young people improve substantially or recover, whereas full recovery in adults is uncommon.

2021 NICE guideline

Treatment

Recommended

A personalised energy management plan

Remains an option

Cognitive behavioural therapy, as supportive treatment for symptom management

Advised against

Graded exercise therapy, the Lightning Process, curative medicines, routine supplements

  • School: a young person who values school should stay in it through flexible adjustments, such as a part-time timetable with rest breaks that respects the energy limit and keeps peer contact.

Physical disease mistaken for psychiatric disorder

Condition

Mistaken for

Points to the physical cause

Hypothyroidism

Depression, slowing, falling attainment

Growth changes, cold intolerance, goitre

Hyperthyroidism, usually Graves' disease

Anxiety, irritability

Tachycardia, tremor, heat intolerance, eye signs

Wilson's disease

Mood, behavioural or cognitive disorder

Liver disease, dystonia, Kayser-Fleischer rings

Anti-N-methyl-D-aspartate receptor encephalitis

Acute psychosis, agitation, catatonia

Rapid progression, seizures, dyskinesia, autonomic change

Niemann-Pick disease type C

Antipsychotic-resistant psychosis, executive decline

Vertical supranuclear gaze palsy

Absence epilepsy

Inattention

Brief impaired awareness, generalised 3 Hz spike-wave on EEG

Obstructive sleep apnoea

Inattention, hyperactivity

Snoring, witnessed apnoeas

Corticosteroids, montelukast, levetiracetam

New mood, sleep or behaviour change

Timing against the treatment

The left panel shows a brownish Kayser-Fleischer ring at the corneal limbus, and the right panel shows the copper-related sunflower cataract; both point to Wilson's disease as the physical cause of mood, behavioural or cognitive change. Imrankabirhossain, CC BY-SA 4.0, via Wikimedia Commons
  • Rapid onset, an unusual age, neurological signs, regression or cognitive decline should raise suspicion of a physical cause. Primary psychiatric illness can also begin acutely.

Epilepsy and brain injury

  • Lennox-Gastaut syndrome is a severe childhood epilepsy defined by multiple seizure types, slow spike-and-wave activity on the electroencephalogram (EEG) and cognitive impairment. Its accompanying psychiatric problems do not define it.

  • After mild traumatic brain injury, children and adolescents repeatedly show depression, anxiety, attention deficit hyperactivity disorder and conduct problems. Mania is not an established outcome.

Count the complexes in the shaded one-second window: Lennox-Gastaut syndrome gives slow spike-and-wave at about 2 per second on a slow background (A), while absence epilepsy gives generalised 3 Hz spike-and-wave that starts and stops abruptly (B). Drawn for MRCPsychiatrist

Constipation

  • Functional (idiopathic) constipation accounts for the great majority of childhood constipation, and no organic cause is found.

  • Hirschsprung's disease is a congenital aganglionosis of the distal bowel and is usually diagnosed within the first two years of life.

Chronic illness, adherence and assessment

  • Missed treatment in adolescence is common and can be dangerous. Assess urgently whether self-harm, eating disorder behaviour or safeguarding concerns lie behind an omission that threatens health.

  • Assess capacity or competence for the actual decision under the law for the young person's age. Gillick is not the test for every 16 or 17-year-old.

  • Physical and psychiatric disorders can coexist, so do not pin every new symptom on the known diagnosis.